Home > Terms > English, UK (UE) > pethidine
pethidine
Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as a hydrochloride salt in tablets, as a syrup, or by intramuscular, subcutaneous or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1975 60% of doctors prescribed it for acute pain and 22% for chronic severe pain. Compared with morphine, pethidine was thought to be safer, carry a lower risk of addiction and to be superior in treating the pain associated with biliary spasm or renal colic due to its putative anticholinergic effects. It was later discovered that these were all myths and that it carried an at least equal risk of addiction, possessed no advantageous effects on biliary spasm or renal colic compared to other opioids and that, due to its toxic metabolite, norpethidine, it was more toxic than other opioids, especially during long-term use.
- Part of Speech: noun
- Synonym(s):
- Blossary: Illegal Drugs
- Industry/Domain: Law enforcement
- Category: Drug trafficking
- Company:
- Product:
- Acronym-Abbreviation:
Other Languages:
Member comments
Terms in the News
Featured Terms
Titanic
The legendary passenger liner that sank after colliding with an iceberg on its maiden voyage from Southampton, England to New York City in April, ...
Contributor
Featured blossaries
stanley soerianto
0
Terms
107
Blossaries
6
Followers
Top 10 Most Venomous Snakes
Browers Terms By Category
- Lingerie(48)
- Underwear(32)
- Skirts & dresses(30)
- Coats & jackets(25)
- Trousers & shorts(22)
- Shirts(17)
Apparel(222) Terms
- Inorganic pigments(45)
- Inorganic salts(2)
- Phosphates(1)
- Oxides(1)
- Inorganic acids(1)
Inorganic chemicals(50) Terms
- American culture(1308)
- Popular culture(211)
- General culture(150)
- People(80)
Culture(1749) Terms
- Industrial lubricants(657)
- Cranes(413)
- Laser equipment(243)
- Conveyors(185)
- Lathe(62)
- Welding equipment(52)
Industrial machinery(1734) Terms
- Contracts(640)
- Home improvement(270)
- Mortgage(171)
- Residential(37)
- Corporate(35)
- Commercial(31)